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Conditions
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Biliary tract diseases
Cholangitis
Primary sclerosing cholangitis

Primary sclerosing cholangitis

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Primary sclerosing cholangitis (psc) is a chronic liver disease caused by progressive inflammation and scarring of the bile ducts of the liver. The inflammation impedes the flow of bile to the gut, which can ultimately lead to liver cirrhosis, liver failure and liver cancer. The underlying cause of the inflammation is believed to be autoimmunity.

Dr. Shady Macaron reviewed this

22 years experience

Is a type of:

Cholangitis

How long it usually lasts:

Chronic (lasts years to lifelong)

How common it is:

Rare

Body locations

Upper abdomen

Symptoms

Fever
Fatigue
Itchy rash
Abdominal pain
Itching or burning
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Medications

Ratings show how effective doctors think these medications are at treating Primary sclerosing cholangitis
Ursodiol
3
5 reviews
Calcitriol
2
4 reviews
Ursodeoxycholate
1
1 review
Calcium supplements
Urso forte
Load more

Procedures

Ratings show how effective doctors think these procedures are at treating Primary sclerosing cholangitis

Surgery

Liver transplant
3.6
8 reviews

Other treatments

Watchful waiting

Tests

ANA
Ceruloplasmin
Prothrombin time
Complete blood count
Total bilirubin
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Related questions

A 22-year old female asked:

Is primary sclerosing cholangitis rare?

1 doctor answer • 10 doctors weighed in

A 37-year old asked:

How can I treat primary sclerosing cholangitis?

2 doctor answers • 8 doctors weighed in

A 35-year old asked:

Primary sclerosing cholangitis - what is the inherited risk?

1 doctor answer • 1 doctor weighed in

A member asked:

Does primary sclerosing cholangitis usually cause many symptoms?

1 doctor answer • 8 doctors weighed in

A 45-year old male asked:

Any information and/or prognosis for Primary Sclerosing Cholangitis , from which I am currently dying?

1 doctor answer • 1 doctor weighed in

A 34-year old asked:

Will primary sclerosing cholangitis kill me?

1 doctor answer • 2 doctors weighed in

A 27-year old asked:

Do people with primary sclerosing cholangitis have a lot of pain?

2 doctor answers • 6 doctors weighed in

A 25-year old male asked:

I'm a 25 year old male recently diagnosed with stage 2 primary sclerosing cholangitis. Is this a common age range for this issue?

1 doctor answer • 4 doctors weighed in

A 39-year old asked:

Primary sclerosing cholangitis---what treatments are best?

1 doctor answer • 1 doctor weighed in

A member asked:

Do doctors see a lot of patients with primary sclerosing cholangitis?

1 doctor answer • 5 doctors weighed in

A 29-year old male asked:

Which tests can I undergo to give me a good overall idea of my health, as well as check for Primary Sclerosing Cholangitis (runs in family)?

1 doctor answer • 1 doctor weighed in

A 47-year old asked:

Is there any relation between ulcerative colitis and primary sclerosing cholangitis?

1 doctor answer • 1 doctor weighed in

A 26-year old male asked:

Is primary sclerosing cholangitis only associated with severe Ulcerative Colitis? Or is it associated with mild disease too?

1 doctor answer • 1 doctor weighed in

A 26-year old female asked about a male:

He has gallstones and maybe with psc (primary sclerosing cholangitis). He's had constant pain in his upper right quadrant for 24hr+. Do we go to emerg?

1 doctor answer • 1 doctor weighed in

A 34-year old female asked:

I was diagnosed with Primary Sclerosing Cholangitis in 2019. My gastroenterologist has tried to put me in Ursotan, but there is a shortage in the country from the manufacturer / supplier. What overall effect in the delay of treating PSC?

1 doctor answer • 1 doctor weighed in

A 24-year old female asked:

Does primary sclerosing cholangitis show up in blood work? I'm itching all over my body. What can I do?

1 doctor answer • 5 doctors weighed in

A 24-year old male asked:

What's the difference between primary biliary cirrhosis and primary sclerosing cholangitis?

1 doctor answer • 2 doctors weighed in

A member asked:

I have a 16 year old female friend with primary sclerosing cholangitis. If she is on the liver transplant list, what is her prognosis?

3 doctor answers • 5 doctors weighed in

A 28-year old male asked:

What is the definition or description of: sclerosing cholangitis?

2 doctor answers • 4 doctors weighed in

A 38-year old asked:

Will sclerosing cholangitis kill me?

2 doctor answers • 5 doctors weighed in

A 40-year old asked:

What are the symptoms of sclerosing cholangitis ?

1 doctor answer • 4 doctors weighed in

A 39-year old asked:

What are all the long-term complications of sclerosing cholangitis ?

1 doctor answer • 3 doctors weighed in

A 21-year old female asked:

Does sclerosing cholangitis cause fusiform dilation of biliary tree or not fusiform? ?

2 doctor answers • 2 doctors weighed in

A 49-year old female asked:

Hello, Is there an antidepressant (natural or not) that can be used for people suffering from primary biliary cholangitis (sensitive itchy liver) ? Thank you?

1 doctor answer • 1 doctor weighed in

A 49-year old female asked:

Is there any no liver toxic antidepressant (natural or not) that can be used for people who cant take any medication because of the disease primary biliary cholangitis ? Thank you?

2 doctor answers • 2 doctors weighed in

A member asked:

What's the best treatment to get rid of cholangitis?

1 doctor answer • 1 doctor weighed in

A 29-year old female asked:

What is cholangitis? My puppy's been diagnosed; I'm worried for her health and worried it's contagious to my family. The vet doesn't think it's lepto

1 doctor answer • 2 doctors weighed in

A female asked:

Is infective cholangitis the same as biliary sepsis?

1 doctor answer • 4 doctors weighed in

A 51-year old male asked:

Does Acute Cholangitis cause hepatitis? If it does, is the hepatitis acute or chronic?

1 doctor answer • 1 doctor weighed in

A 27-year old female asked:

Does cholangitis cause thrombosis?

2 doctor answers • 5 doctors weighed in

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