A member asked:

Will sclerosing cholangitis kill me?

5 doctors weighed in across 2 answers

SC is serious stuff: Acute attacks of cholangitis may be complicated by bacterial infection of bloodstream with shock & abscesses; rupture of pus-filled bile ducts into the abdomen or fistulizing to GI tract, abdominal wall, or heart sac: clotting of the portal vein; or bleeding from the bile duct. Acute pancreatitis occurs in 10% of patients with relapsing disease, & there can be increased risk of bile duct cancer.

Answered 6/10/2014

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Dr. John Fung answered

Specializes in General Surgery

PSC is progressive: You do not state whether your sclerosing cholangitis (sc) is primary or secondary, primary sc is an autoimmune disorder where the bile ducts become inflamed, leading to blockage of bile flow leading to liver damage. Secondary sc is due to other type of bile duct injury, but blockage leads to liver damage. Psc is progressive, ssc can only be treated if the blockage is relieved. See a hematologist.

Answered 9/4/2013

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