How can i treat primary sclerosing cholangitis?

Difficult problem: Psc: autoimmune swelling/scarring of bile ducts within and outside the liver; often associated with infl. Bowel (usually ulc colitis). Increased risk for biliary ca. Med rx for itch, biochem abnormalities, e.g. Urso (bear bile), antihistamines, antibiotics for infections, vitamin supllements for deficiencies. Ercp procedure may open some strictures (narrowing). Ultimately, may need liver transpla.

Ursodiol: Standard treatment includes ursodiol, a bile acid naturally produced by the liver, which has been shown to lower elevated liver enzyme numbers in people with psc, but has not improved liver- or overall survival. Invasive approaches include ERCP and stunting are needed to open major blockage. Liver transplant is the only proven long term treatment.