Do people with primary sclerosing cholangitis have a lot of pain?

Depends: Primary sclerosing cholangitis ( psc) causes destruction of the bile ducts inside and outside of the liver. The first symptoms of the disease include fatigue, itching and jaundice, or yellowing of the skin and eyes. Psc however, is associated with a number of hepatobilliary disorders like pancreatitis, which may cause pain.

Not common: Most people with psc don't routinely complain of pain. Psc affects the bile ducts and can lead to cirrhosis of the liver. This can cause many things jaundice, itching, fatigue, bleeding. I suppose if you still have your gallbladder you could have some pain from obstruction of the outflow of the gallbladder. But pain isn't the first thing i think of with psc.