What's the best depression medication that won't cause weight gain or could cause low sex drive?

Wellbutrin (bupropion): Again, wellbutrin (bupropion) is a good antidepressant that's not likely to cause weight gain -- and it's also unassociated with sexual dysfunction. In fact some doctors have prescribed it along with other antidepressants in hopes of countering ssri-related sexual dysfunction. Watch the alcohol you're drinking for both of these potential effects, though. Discuss with your own physician.

Wellbutrin (bupropion): Wellbutrin (bupropion) would best since you are on tryptans. Also do not drink while on antidepressants and make sure you are in psychotherapy. Good luck to you.