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A 42-year-old member asked:

what are the side effects of lupron (leuprolide)?

3 doctor answers4 doctors weighed in
Dr. Philip Chenette
Fertility Medicine 38 years experience
Headaches: Headaches and hot flashes are the most common side effects of Lupron (leuprolide) when used short term.
Dr. David Finke
Obstetrics and Gynecology 15 years experience
Avoid them with...: Norethindrone acetate, or aygestin (norethindrone). If you are taking lupron, the most serious side effect of longer term use is bone weakening, or osteopenia. You can avoid the majority of this bone loss and avoid most hot flashes with daily oral "add-back therapy" with Norethindrone acetate. When you stop taking lupron, most of the bone loss is recovered quickly.
Dr. Michael Fox
Fertility Medicine 34 years experience
Terrible: Lupron (leuprolide) causes reversible menopause. So as soon as the medicine takes effect the estrogen drops to zero same as complete menopause. Hot flashes, night sweats, moods, memory issues and joint pain etc. Many dr.S use this for endometriosis but endo is a surgically treated disease. Lupron (leuprolide) only temporarily diminishes symptoms but makes people miserable. Excisional surgery is needed via laparoscopy!

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CA
A 35-year-old member asked:

What are the side effects of lupron (leuprolide) depot ?

2 doctor answers5 doctors weighed in
Dr. Neeoo Chin
Fertility Medicine 40 years experience
Side effects: Lupron (leuprolide) side effects are hot flashes and head aches. If taken for longer than 6 months some reversible bone loss can be found with bone scans.
A 39-year-old member asked:

Lupron (leuprolide) shot and side effects?

1 doctor answer7 doctors weighed in
Dr. Michael Murray
Fertility Medicine 28 years experience
Hot Flashes: By far, the most common side effect is hot flashes, because Lupron (leuprolide) causes a temporary menopause. Poor sleep resulting in emotional side effects or head ache are also common. A serious effect from long-term Lupron (leuprolide) is osteoporosis. Many of these side effects are reduced or eliminated with extra "add-back" hormones. Some women have no side effects at all.
A 42-year-old member asked:

How severe do the side effects of lupron (leuprolide) depot?

1 doctor answer1 doctor weighed in
Dr. Michael Traub
Fertility Medicine 19 years experience
Usually Mild: When i treat patients with Depo-Provera Lupron (leuprolide) (for instance for endometriosis) i usual;y use add back therapy, this is a second medicine used to prevent the side effects from lupron (leuprolide). The addback usually reduces or gets rid of any hot flashes, any vaginal dryness, or any mood swings. So in this way i usually prevent side effects from ever occurring.
A 47-year-old member asked:

What are lupron (leuprolide) side effects with existing conditions?

1 doctor answer1 doctor weighed in
Dr. Gerard Honore
Fertility Medicine 29 years experience
Unclear?: I'm not certain what you are asking, but side effects 'with' conditions would be the same as 'without' conditions: mainly hot flashes, vaginal dryness, eventual bone loss.
A 36-year-old member asked:

Can the side effects of lupron (leuprolide) be reversed?

1 doctor answer2 doctors weighed in
Dr. Timothy Raichle
Obstetrics and Gynecology 22 years experience
Yes: If you are currently on lupron, (leuprolide) there are commonly side effects such as hot flashes. These can easily be treated with supplemental hormones. The most commonly used hormone is progesterone. Many physicians will start with norethindrone, 5mg per day. Good luck!

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Last updated May 9, 2018

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