A member asked:

On lupron (leuprolide) for fibroids and endo, also taking 2mg estrace as addback. started spotting and bleeding, 20 days now. why? can estrace make fibroids grow?

A doctor has provided 1 answer
Dr. Gerard Honore answered

Specializes in Fertility Medicine

Doubtful, but: Estrace is estradiol (common estrogen) so it stimulates the endometrium. I'd 100% expect spotting on Lupron/Estrace, heavy bleeding not so much. Ask your prescribing doctor for further information, hope this helps you.

Answered 12/16/2014



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