A member asked:

Is xanax (alprazolam) okay to take with fentanyl?

8 doctors weighed in across 2 answers

With supervision: The sedative effects of these drugs can have an unsafe synergistic effect. If taken in combination, it should be under a doctor's supervision.

Answered 12/30/2016

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Possibly: The drugs can be used together but the sedative and possible respiratory depression risks are increased by concomitant use. They should only be used together if prescribed by the same physician and then only as directed.

Answered 10/28/2013

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