Get Virtual Care
For Businesses
About Us
A member asked:
Is it dangerous to combine melatonin and unisom?
7 doctors weighed in across 2 answers
No.: There are no known drug interactions at the recommended doses. Unisom is the brand name for diphenhydramine, an antihistamine. It also has anticholinergic and cough suppressant properties. Melatonin works on your pineal gland to help promote a regular sleep cycle. Be aware of potential overssedation when taking both at high doses.
Answered 5/4/2018
4.8k views
Melatonin/Unisom: Not advised, due to excess sedation. Using one or the other at adjusted dose as prescribed, would be better option.
Answered 11/28/2017
2.8k views
Related Questions
A member asked:
My friend took 60mg of melatonin. How dangerous is that? How much can someone take before it reaches dangerous levels?
A doctor has provided 1 answer
A member asked:
Why does tasimelteon elevate liver enzymes, and is it dangerous or more dangerous than melatonin?
A doctor has provided 1 answer
A member asked:
I have been taking supplements vitamin e, melatonin, and fish oil every day along with claritin. Are any of these dangerous to be combining?
A doctor has provided 1 answer
A member asked:
Ive treated anxiety induced insomnia with talk & somatic therapy but still fall asleep fine but wake up at 2 or 3 am and cant fall back to sleep. Used mezclizine nearly nightly for years to help. Is this dangerous? Alternatives? Melatonin not help?
2 doctors weighed in across 2 answers
A member asked:
Accidentally took two unisom sleep tablets - dangerous?
A doctor has provided 1 answer
People also searched for:
Can I take two unisom and a melatonin together?
Is it okay to take unisom natural nights sleep aid(contains vitamin b, calcium, and melatonin)4 hours after taking cipro (ciprofloxacin)?
Will taking unisom natural nights sleep aid(contains calcium, vitamin b, and melatonin) 4 hours after taking cipro (ciprofloxacin), (cipro (ciprofloxacin)floxacin) make the cipro (ciprofloxacin) less effective?
Is it dangerous to overdose on melatonin? What happens if overdose? How much at once is considered overdose for a 95lb Female? How much should I take?
Dangerous to use melatonin and diphenhydramine?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Download HealthTap
Video visit and message your doctor
