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A 21-year-old member asked:

Can neurofibromatosis type 1 progress to neurofibromatosis type 2?

3 doctor answers10 doctors weighed in
Dr. Cristina Carballo
Dr. Cristina Carballoanswered
Neonatology 39 years experience
No: Two distinct diseases caused by different genetics.
Dr. Addagada Rao
General Surgery 56 years experience
NO : Tow distinct gene mutations. Neurofibroma nf i & nf ii are both inhirted tppe i will show cutaneous, neurological and ortho malformations.Tend to be non cancerous nf ii is less frequent ( i in 40000 ) less skin lesions more neuroligical tumors, like maningiomas, bil aucoatic neuromas, schiwanomas, gliomas is part of misme syndrome.
Dr. Gerald Mandell
Nuclear Medicine 52 years experience
Rare: Extremely rare to have nf1 and nf2 at same time. Not sure if this combination has been reported.

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