A member asked:

Can neurofibromatosis type 1 progress to neurofibromatosis type 2?

10 doctors weighed in across 3 answers
Dr. Cristina Carballo answered

Specializes in Neonatology

No: Two distinct diseases caused by different genetics.

Answered 9/28/2016


Dr. Addagada Rao answered

Specializes in General Surgery

NO : Tow distinct gene mutations. Neurofibroma nf i & nf ii are both inhirted tppe i will show cutaneous, neurological and ortho malformations.Tend to be non cancerous nf ii is less frequent ( i in 40000 ) less skin lesions more neuroligical tumors, like maningiomas, bil aucoatic neuromas, schiwanomas, gliomas is part of misme syndrome.

Answered 6/25/2020


Dr. Gerald Mandell answered

Specializes in Nuclear Medicine

Rare: Extremely rare to have nf1 and nf2 at same time. Not sure if this combination has been reported.

Answered 8/17/2014



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