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A 30-year-old member asked:

Can you take 2 benadryls (diphenhydramine) and a mucinex melt?

2 doctor answers3 doctors weighed in
Dr. Sunil Mehra
Pulmonology 44 years experience
You can at your age: Yes you can take this combination but be careful cause of sleepiness and tired feeling with benadryl (diphenhydramine).
Dr. Thomas Hansbrough
ENT and Head and Neck Surgery 44 years experience
Yes, if adult: Assuming the Benadryl (diphenhydramine) is 25mg per capsule, it is ok to take 2 with plain Mucinex for relief of cold symptoms with thick mucus drainage for adults. Realize that Benadryl (diphenhydramine) may cause sedation and should not be used if the individual will be driving or operating machinery.

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Similar questions

Belleville, MI
A 42-year-old female asked:

Can i take Mucinex dm and Benadryl (diphenhydramine) together?

1 doctor answer2 doctors weighed in
Dr. John McMahan
ENT and Head and Neck Surgery 48 years experience
Medician Question: This combination could make you very sleepy so be careful - in some cases there could be serious consequenses. See your doctor for more definitive treatment of your cough.
AR
A 36-year-old female asked:

Can i take a benadryl (diphenhydramine) & Mucinex night together?

1 doctor answer2 doctors weighed in
Dr. William Coutts ii
Family Medicine 26 years experience
Yes: Benadryl (diphenhydramine) will help you sleep and help with excess mucus production. Mucinex (guaifenesin) is called an expectorant as it helps thin and loosen mucus to make your cough more effective at clearing the mucus from your lungs. There should be no problem taking these two medications together.
A 45-year-old member asked:

I just took a mucinex. Will i be okay if i take Benadryl (diphenhydramine) as well?

1 doctor answer1 doctor weighed in
Dr. Yash Khanna
Family Medicine 57 years experience
Not a good idea: You have to know Mucinex help thin the phlegm and Benadryl (diphenhydramine) has drying effect on mucous or phlegm, so you are defeating the purpose of taking musinex if you need to take antihistamine with Mucinex for allergy, i will recommend takind over the counter Claritin which may not be as drying as benadryl, (diphenhydramine) and dont forget to drink lot of fluids.

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Last updated Jun 20, 2019

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