Botox: Takes 2-5 days to kick in.
Answered 9/13/2013
4.9k views
About a week: It can take between5-7 days for Botox to work on the muscle. It does not mean that your piriformis syndrome will be gone at 1 week. Once the muscle are relaxed the physical therapy can be utilized.
Answered 6/24/2014
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