SFI: Sporadic fatal insomnia is a very rare, transmissible neurodegenerative disease characterized by the accumulation of a misfolded protein (the prion protein) in the brain. Symptoms include disrupted sleep, autonomic dysfunction, and motor abnormalities including myoclonus, ataxia, dysarthria, dysphagia, and pyramidal signs like clonus on exam. There may be peculiar behaviors too.
Answered 12/3/2015
4.9k views
SFI: Only 8 cases have ever been diagnosed as of july 2005, so it is extremely rare.
Answered 1/20/2016
4.9k views
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A doctor has provided 1 answer
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A doctor has provided 1 answer
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