No real difference: Both are nsaids and both have the same mechanism of action. Motrin (ibuprofen) tends to be shorter acting and needs to be taken every 4-6 hours while Aleve (naproxen) is longer acting and needs to be taken every 12 hours. Both will work for the knee pain.
Answered 10/26/2016
6k views
Varies by person: Motrin, Aleve or tylenol (acetaminophen) might work best depending on the individual.
Answered 9/28/2016
6k views
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