What We Treat
Telehealth
About Us
- Features & Pricing
- For Organizations
A member asked:
If i have the single gene mutation (heterozygote) and am a "silent carrier" for hemochromatosis, will i become iron overloaded?
6 doctors weighed in across 2 answers
Hemachromatosis: The single gene carrier will likely not develop any symptoms or problems from increased iron absorption. You will still need to have regular blood work to check for increased iron, and not use any supplements with iron. If you have two genes, your chance is good that you will have high levels of iron, and possibly get damage from the extra iron. Timing is unknown, too many variables.
Answered 5/3/2019
6.1k views
No: Hereditary hemochromatosis develops when you inherit two mutations, one on each of your hfe genes. You have just one. About 1/10 folks with northern european ancestry is a carrier. Carriers don't get iron overload. In fact, most folks with two hfe mutations do not get sick at all, even though for many we can see that they are accumulating a lot of iron. A mystery? Rather. But we're working on it.
Answered 1/9/2020
5.5k views
Related Questions
A member asked:
Low folic acid &high iron sat per me. Have 1 mutation for hemachromatosis.Petichiae on arms. Any suggestions 're what to ask doctor about?
8 doctors weighed in across 2 answers
A member asked:
Hemochromatosis - do I have to be a gene carrier to have symptoms? My gastro is just ck for gene not actual blood levels. Seems he may be skip a step?
A doctor has provided 1 answer
A member asked:
I'm 25&Male, Rbc=5.9(H),hb=15.5,mch=26.3(L) Mpv=13.7(H),hct =47%, iron=80,Tibc=260,ferritin=250.4(ref:20-250),have i a iron overload?(hemochromatosis)
A doctor has provided 1 answer
A member asked:
Does hemochromatosis ever cause compensatory hyperventilation? Does this signal that heart damage from iron overload is already done?
4 doctors weighed in across 2 answers
People also searched for:
If I have the double gene mutation (homozygous) for hemochromatosis but am not clinically iron overloaded (have high iron levels on lab results) at this time, can I develop iron overload later, such as in 2, 5, or 10 or more years later?
I tested positive for hemachromotosis genetic mutation. My iron levels were high but ferritin was only 50. I'm 19. Should I avoid iron in food?
Isn't the diagnosis for hemochromatosis based on irish hemochromatosis? Other races like far east have different gene for iron overload
How can I know if I have iron overload/hemochromatosis? What tests should be performed? I hear that there is a DNA genetic test kit for hemochromatosis, is that true?
What is a hereditary hemochromatosis DNA mutation?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Get the HealthTap app
Video visit and message your doctor
