What's good for poison ivy and poison oak?

Steroids: These reactions represent a contact allergy, and can be quite severe. The affected area needs to be washed thoroughly, and topical steroid creams can be applied. You can start with 1% Hydrocortisone from the drug store, but a more potent prescription cream will probably be necessary. In severe cases, oral Prednisone my be required.

Wash it off: Most important is to wash the juice off your skin as soon as possible. Cool soaks or ice packs can help. Hydrocortisone cream or anti-itch products like calamine, itch-x, etc. May help. Beyond that you may need prescription medication.