A member asked:

Is there any synergism between diazepam at nite and duloxetine in am?

A doctor has provided 1 answer
Dr. TRUC DAO answered

Valium, cymbalta (duloxetine): Yes! a pill of Valium work for 72 hours! though its effect is mainly felt the first 24h. Both together synergistically aggravates daytime sleepiness. A lot of people taking Cymbalta (duloxetine) in the morning feels sleepy, yawns ++ then the pill is switched to night use to directly help people sleep better. Not all people feels sleepy with it though, and most people take it in the morning.

Answered 1/5/2020

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