Fetal alcohol: The deleterious effects of ethanol on the developing human brain are poorly understood. Here it is reported that ethanol, acting by a dual mechanism [blockade ofn-methyl-d-aspartate (nmda) glutamate receptors and excessive activation of gabaa receptors], triggers widespread apoptotic neurodegeneration in the developing rat forebrain. Vulnerability coincides with the period synaptogenesis.
Answered 4/13/2012
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First of all...: ...Alcoholics frequently deny that they drink; so if there are features suggesting fas, you have to be sure the mother really is a non-drinker. That said, cornelia de lange syndrome, velocardiofacial syndrome (vcfs), & dubowitz syndrome - & probably others - share features with fas, though they are rarer. A precise diagnosis requires a thorough exam and lab testing by an expert in this field.
Answered 4/30/2016
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