If swollen lymph nodes emerge from an inflammatory process like lupus (autoimmune disease) would ibuprofen an nsaid make then go away?

Lupus: We need to treat the clinical manifestation of your lupus. Some cases are mild some are complex. Your doctor needs to work up your "inflamed lymph node".

No.: Lymphadenopathy (large nodes) if do to sle, will not go away with nsaids. See your rheumatologist if this persists.

Monitoring Centers: Lymphatic system absorbs/carries things too big to go into the arteries/veins like bacteria eaten by white cells and digested food. Lymph nodes "taste" the lymph for anything bad like bacteria/viruses/cancers, etc. When it detects a problem, it alerts the immune system and your body reacts. They enlarge in response to the inflammation they create when they react. They shrink when all is well.