A 20-year-old male asked:
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i take 60 mg of vyvanse along with 30 mg of lexapro (escitalopram) daily. what is the likelihood of developing serotonin syndrome? how deadly is it?

2 doctor answers
Dr. Alan Ali
Dr. Alan Ali answered
32 years experience Psychiatry
Vyvanse (lisdexamfetamine): If u have been on the medications foa a while and tolerating them well, unlikely. Let your prescriber be aware of your concerns.
Answered on Oct 21, 2013
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Dr. Alfred Forrester
42 years experience Psychiatry
Not likely: If you are asking if the combination of vyvanse and Lexapro (escitalopram) would be more likely than Lexapro (escitalopram) alone to cause serotonin syndrome, i would say 'no': vyvanse's effect doesn't involve serotonin. Statistically, use of large amounts of one med or the combined use of several meds which increase serotonin could lead to S.S. A 30mg dose of Lexapro (escitalopram) shouldn't - but combining that w. Other sero. Meds could.
Answered on Jun 10, 2018
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