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A 49-year-old male asked:

Oddly enough, dr has noticed that i'm extremely sensitive to ssri's for depression. i react to them negatively in like 2- 3 days. any new treatments?

2 doctor answers4 doctors weighed in
Dr. William Singer
Pediatric Neurology 51 years experience
Old treatments: Talk to your doctor about some older antidepressant mess such as the tricyclics. They are generally tolerated. Their main side effect is sedation so they are usually given just befor bd time.
Dr. William Lizarraga
Internal Medicine 16 years experience
Several besides ssri: Other medicines exist, including snris like venlafaxine or duloxetine. Wellbutrin (bupropion) does not affect serotonin receptors and might work well too. These are not new drugs. Non pharmacological means of treating dression should also be considered, like therapy especially.

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Last updated Nov 6, 2014

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