No: Levothyroxine is best taken in the morning on an empty stomach for maximal absorption. Aleve is an over the counter non-steroidal anti-inflammatory drug containing naproxen, which is best taken with food to avoid gastric irritation. Since both are metablize by different pathway, there is no significant interaction. However, to have maximal therapeutic effects, timing of medicines should be done.
Answered 1/18/2020
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Drug interaction: There are several free drug interaction checkers you can use online. There is no drug interaction between levothyroxine and aleve (naproxen).
Answered 4/2/2019
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