A member asked:

If i take metformin and orlistat together how much weight will i lose?

3 doctors weighed in across 3 answers

Eat less and the: Pounds will fall off. Walk at least 60 min every day , no more sodas or deep fried food or white bread the rest of your life! good luck and persevere!

Answered 7/10/2017

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Dr. Milton Alvis, jr answered

Specializes in Preventive Medicine

Very Little Wt ↓:: Metformin, in long published clinical trials, has no tract record of wt ↓. Orlistat drives only a little wt. ↓, accompanied with GI gas, steatorrhea/frequent urgent bowel movements & whatever wt ↓ rarely lasts at 1 year. For better information study my answers, Big Fat Lies, Gary Taubes, Peter Attia, FatChance.html, Science for Smart People, NUSI.org, Jacques Peretti, http://goo.gl/yxoOWD, etc.

Answered 9/27/2014

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Dr. Parul Krishnamurthy answered

Specializes in Obstetrics & Gynecology

Metformin may help: Metformin may assist weight loss in some patients initially, especially when combined with dietary discretion and exercise

Answered 2/24/2020

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