I woke up with a painful burning sensation in my palm, both hands. fingers not so much but carea closer to wrist is flaming! please advise thank you?

Periph. neuropathy: Sounds like the onset of a peripheral neuropathy which can be related to underlying diseases, spinal cord arthritic changes with pressure on nerve endings, or spinal cord lesions themselves. You need to see and be evaluated by a neurologist and would do this asap as the longer nerve conditions persist the slower the resolution. Good luck.