Ocd, am taking 300 mg luvox and still going back to house to check locks after leave, also on abilify, (aripiprazole) remeron and depekote for bipolar i, what next?

Psychotherapy: What's "next" might be to add psychotherapy to your current treatment -- specifically cognitive behavioral therapy, with exposure and response prevention (erp). This can be really helpful, and increases likelihood of good results for ocd treatment. Speak with your psychiatrist about such referrals. More info here: http://www.Ocfoundation.Org/cbt.Aspx.

End of the road?: Try talk therapy if you can find a good one willing to take a stab at ocd. It is a challenge (as you may know better than most), so be patient. It might take lots of time, effort and courage, but it is possible to master these kind of symptoms. It helps if you can use your best abilities to take a lighter perspective - a bit of wit. Best wishes in your struggle.

Talk therapy: Trying to manage/treat OCD symptoms with medication alone is often insufficient. Seek out a qualified cognitive behavioral and/or mindfulness therapist.