A member asked:

I take 25mg zoloft, 100mg metoprolol tartrate, and 50 mg xanax (alprazolam) as needed. i did take a xanaz last night and 120 mg oxycodone. whole day i was out of it and dizzy, unable to do anything. is this norma?

2 doctors weighed in across 2 answers

Dangerous, not norma: If you take zoloft, i'm assuming 0.5 mg of xanax, (alprazolam) 50 mg of metoprolol and 120 mg of oxycodone, a lot would depend upon whether you are used to taking that much oxycodone. If your body is used to it and you gradually raised up to that dose than there would likely be no difficulties. However, if you suddenly added in 100 mg of oxycodone, you could have overdosed on that. A lot also depends upon your body's ability to tolerate sedatives in general and whether you have underlying sleep apnea as a medical condition. I would highly recommend that you talk to your prescribing physician about the dose of oxycodone and in particular how quickly you raised up to that dose. You should never take more pain medication than prescribed. It is the type of situation where people accidentally overdose and die in their sleep.

Answered 9/14/2020

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As I understand : You took xanax (alprazolam) and one dose of 120 mg of ocycodone together before going to sleep. If I am right that was a very dangerous combination. Oxycodone 80-100mg a day in divided doses is a fairly high dose for a narcotic naive patient. Don't know if you have chronic pain syndrome and use oxycodone for that. But, that dosing was a very dangerous one. The combination can be lethal. Stop and look for help!

Answered 6/2/2018

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