A member asked:

Is parnate (tranylcypromine) dangerous?

5 doctors weighed in across 3 answers

Parnate (tranylcypromine): It is an antidepressant in the group known as monoamine oxidase inhibitors. It has risks related to all maoi usage, and should be monitored by a physician.

Answered 2/23/2018

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Parnate: Parnate (Tranylcypromine) is a monoamine oxidase inhibitor antidepressant. here is a significant danger of a hypertensive crisis if one takes Parnate and eats food containing Tyramine.

Answered 2/1/2021

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Dr. James Schlichting answered

Specializes in Medical Psychotherapy

Parnate (Tranylcypromine) is a monoamine oxidase inhibitor that is used for depression or social anxiety when SSRIs or SSNRIs have been tried and are not effective. The major concern here is that a hypertensive crisis can occur if the patient ingests tyramine from food/drink like aged cheese, a beer on tap, and more. This, the side effect profile + black box warning requires strict physician care

Answered 3/23/2023

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