A member asked:

How unsafe is it to mix effexor (venlafaxine) with recreational drugs?

A doctor has provided 1 answer
Dr. Patrick Tapia answered

Specializes in Psychiatry

Yes: The scariest possibility is that the propensity of Effexor (venlafaxine) to elevate blood pressure without the presence of recreational drugs would be potentiated in the presence of any substance with a capacity for elevating blood pressure to the point of producing a catastrophic event such as a cerebrovascular hemorrhage. Also there is serotonin syndrome and hyponatremia in addition to severe behavior change.

Answered 12/22/2014

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