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A member asked:
Can avapro (arb), tekturna (aliskiren) hctz (dri-hctz) & lotrel (ccb-ace1) be used together for high blood pressure? i know together they can cause hyperkalemia.
3 doctors weighed in across 3 answers
Perhaps but...: Perhaps, but in my experience the additive effects in bringing blood pressure down are not great. Also benefits of tekturna (aliskiren) are lacking especially in diabetics.
Answered 10/24/2018
6k views
Overkill: Ace/arb/ dri all work on the raas system. Novartis recently released the altitude study where they studied the effects of the combination of Diovan and tekturna (aliskiren) in diabetics with renal disease. Renal function worsened. Due to that I have stopped using those together. Now novartis is no longer promoting the tekturna (aliskiren) family of products and will be laying off 60% of their sales force in april.
Answered 10/24/2018
6k views
Different meds: ARB, ACE-I,Tekturna (aliskiren) all act on one hormonal axis- renin-angiotensin- aldosterone axis. Yes, this combination can cause hyperkalemia. Usually, medicines with different modes of action ( act at different pathways) are preferred to get the maximum benefit
Answered 10/24/2018
3.6k views
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