After took panadol (acetaminophen) cold and flu (paracetamol, phenylephrine hydrochloride), can i take actifed afterwards (triprolidine hydrochloride, pseudoephedrine?

Wait 4 hrs: You should wait 4 hrs because of the potentially additive effects of the decongestants present in both compounds particularly important if you have high blood pressure.

No: You shouldn't use both at the same time. If you want to switch from one to the other, wait until it is time for your next dose of the panadol, (acetaminophen) but then take the actifed instead. They are different medicines, but act in almost exactly the same fashion, so taking them together will result in too high a dose.