A member asked:

What predisposes someone to major depression?

17 doctors weighed in across 2 answers
Dr. William Holmes answered

Specializes in Child Psychiatry

Multiple Factors: There are several factors that may increase the risk of depression. One of these is a strong family history of severe depression. Also, negative life experiences such as trauma, abuse, and multiple losses can increase this risk. Chronic pain and other medical conditions can play a role, as well as the abuse of substances such as alcohol and illegal drugs.

Answered 9/17/2018

6k views

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Dr. Alan Ali answered

Specializes in Psychiatry

Depression: Biopsychosocial factors, mainly genetic (biological), self concept & esteem issues (psychological) and stress (social). This is one model, simplified to explain causes of depression.

Answered 10/4/2016

5.6k views

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