No: If a blister is intact do not open or drain it. An unopened blister acts as nature's bandaid. The liquid acts as a burn material, helping the underlying skin heal. If using antibiotic ointment be certain not to use neosporin for prolonged time (over 3 days) as the neomycin can cause skin sensitization and actually make the skin red and irritated.
Answered 9/7/2019
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No protect it: An unpopped blister represents a closed sterile environment. Yes on occasion one can become infected then it is time to open it, however the risk of infection in a dressed open wound is still higher than that of an intact blister. The blister will gradually resolve with time.
Answered 12/10/2013
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