A member asked:

If both my girlfriend and i have sickle cell trait, what will it mean for us? what are the chances of having a healthy kid? we're both 22

13 doctors weighed in across 4 answers

Genetic odds: Each of you has a 1/2 chance of passing either the sickle gene or the normal gene to a child.This means that 25% with have both abnormal genes, 50% will have one abnormal and one normal (they will have trait like you and your girlfriend) and 25% will inherited both normal genes. It looks like ss;sn:ns:nn. 25%:25%:25%:25%.

Answered 9/15/2013

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Dr. Bahman Omrani answered

Specializes in Pain Management

Genetics : If both posses the common sickle cell trait you'll have a 25% (1 / 4) chance of delivering a baby with sickle cell disease. So the odds are on your side. Make an appointment with a genetics counselor; there is a lot more to it.

Answered 12/9/2013

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Dr. Michael Engel answered

Specializes in Pediatric Hematology and Oncology

Provided both are Ss: Which means you are heterozygous for the hgbs mutation (one normal beta chain and one sickle cell mutant beta chain), then mendelian genetics define risk for having disease, trait, or normal. You have a 25% chance of having a child with sickle cell, a 25% chance of no disease, and a 50% chance of your child having trait. Disease severity is affected by other intrinsic and extrinsic factors.

Answered 10/4/2016

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Dr. Ihab Ibrahim answered

Specializes in Pain Management

1/4: 25 % chance. http://my.clevelandclinic.org/disorders/sickle_cell_anemia/hic_sickle_cell_anemia.aspx.

Answered 10/4/2016

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Related Questions

A member asked:

Could two people with sickle cell trait give their child sickle cell anemia?

3 doctors weighed in across 2 answers