Middletown, NJ
A 32-year-old female asked:
Severe narcolepsy (no cataplexy) and recent findings of pmdd not mdd. stims help but lose effectiveness. pristiq (desvenlafaxine) dn work. super fit but bad apathy?
1 doctor answer • 4 doctors weighed in

Dr. Bennett Machanicanswered
Neurology 54 years experience
Unusual?? Hmm!: Unusual for the meds used in narcolepsy to develop tolerance or tachyphylaxis, and much of what you describe involves psychiatric symptomatology. Believe you should first see a psychiatrist, and also, get an overnight sleep study. I am not convinced that your diagnosis is complete.
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Last updated Jul 19, 2013
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