A member asked:

How come i have multiple sclerosis, but nobody else in the family has it?

3 doctors weighed in across 3 answers

Genes only one part: While there are some genetic susceptibilities to ms, the true reasons while one person develops the disease and another does not remain unclear. Family history is only a risk factor, and not a definite predictor, with other factors such as nutrition, infection, and so forth likely playing a role.

Answered 9/19/2013

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Various causes of MS: Both genetic and non-genetic factors are thought to contribute to ms. A person may have had different environmental exposures than their family, or their genetic risk may reflect a combination of risks from the parents. Other family members may not have gotten that same exact combination of risks.

Answered 7/5/2012

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Combination of event: You have a genetic susceptibility, and have encountered environmental triggers which have caused your outcomes. However, usually does not run in families as is not a genetic disorder.

Answered 8/16/2014

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