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A member asked:
If i'm allergic to codeine will i be allergic to percocet as well?
4 doctors weighed in across 2 answers
Codeine: Codeine and Percocet can both trigger itching and hives as they release histamine from the mast cells in the skin in a non-specific manner.
Answered 6/30/2014
5k views
? tolerance issue ?: In true Codeine allergy, risk of cross-reactivity w/ another opioid can be reduced if analgesic of a different class is used. There are 3 chemical classes of opioid analgesics: phenanthrenes, phenylpiperidine, & phenylheptanones (diphenylheptanes). Codeine & oxy are phenanthrenes which means risk of cross reactivity is high. However, majority do well staying in same class, unless life threatening.
Answered 6/24/2014
5k views
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