A 40-year-old member asked:
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if i'm allergic to codeine will i be allergic to percocet as well?

2 doctor answers
Dr. Nayla Mumneh
28 years experience Allergy and Immunology
Codeine: Codeine and Percocet can both trigger itching and hives as they release histamine from the mast cells in the skin in a non-specific manner.
Answered on Jun 30, 2014
Dr. Bahman Omrani
16 years experience Pain Management
? tolerance issue ?: In true Codeine allergy, risk of cross-reactivity w/ another opioid can be reduced if analgesic of a different class is used. There are 3 chemical classes of opioid analgesics: phenanthrenes, phenylpiperidine, & phenylheptanones (diphenylheptanes). Codeine & oxy are phenanthrenes which means risk of cross reactivity is high. However, majority do well staying in same class, unless life threatening.
Answered on Jun 24, 2014

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Dr. Romanth Waghmarae
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?better: I would have to ask "better for what purpose"?
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