How to stop depersonalization during times of anxiety?

Many ways: First step is to get treatment for your anxiety -- therapy can help. A good evaluation is needed. Sometimes meds are helpful, but talk therapies come first. Meditation as a lifestyle approach on your own. When anxious, deep, slow breathing that expands your belly as you breathe and relax. Consciously feel your feet on the ground, or your body in the chair. Focus on present moment sensation.

Depersonalization: This defense allows you to avoid situations or people you are likely threatened by, try to understand and become aware of the typical triggers that cause this reaction. Consult with a mental health professional who can help you learn more about your defense and how to develop healthier coping strategies. Best wishes.