A member asked:

I took myself off methotrexate for psoriatic arthritis without my doctor knowing it. i was on arava and enbrel and my enzymes were slightly elevated. i want to see if psoriasis comes back. if it does and my enzymes go down, i will start start the medicine

7 doctors weighed in across 2 answers

Yes and no: I do believe meds need to be adjusted if liver enzymes are elevated. I also personally do not use Arava (leflunomide) and Methotrexate together because of just this issue. However, i never encourage patients to stop meds without discussing issue with the doctor first.

Answered 3/11/2023

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Dr. Robert Lowe answered

Specializes in Pediatric Rheumatology

No, bad idea: You are on the same team as your doctor. Use your doctor as a consultant to help you make the best decisions for your care. If you alter your treatment plan yourself, you are at the very least putting yourself at risk for a flare of disease, and at worst putting yourself into danger if your medicines require a taper to be done safely. Call your doctor now--tell him/her you'd like to stop your meds.

Answered 1/5/2015

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