A member asked:

Can problems with the classical complement pathway cause bone pain either directly or indirectly?

A doctor has provided 1 answer
Dr. Ihab Ibrahim answered

Specializes in Pain Management

Yes: http://medical-dictionary.thefreedictionary.com/_/dict.aspx?rd=1&word=complement+deficiencies. It is thought that the complement system might play a role in many diseases with an immune component, such as arthritis, barraquer-simons syndrome, asthma, lupus erythematosus, glomerulonephritis, autoimmune heart disease, multiple sclerosis...

Answered 9/28/2016

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