A member asked:

Is there evidence showing oxycodone, vicoden & more alike do not wrk w/o acetaminophen?

3 doctors weighed in across 2 answers
Dr. Richard Pollard answered

Specializes in Anesthesiology

No: The combination of narcotics and nsaids is an attempt to improve the efficacy of each drug. They both work well on their own, but together the effect is greatly increased.

Answered 4/24/2015

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Not true: They work just fine without the acetaminophen. There is some thought that the Acetaminophen enhances the efficacy.

Answered 9/1/2019

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Related Questions

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How strong is tylenol (acetaminophen) #3 compared to roxicodone?

A doctor has provided 1 answer

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