A member asked:

Infant with bite marks in red blood cells. what can cause this?

3 doctors weighed in across 2 answers

G6PD deficiency: This is a classic term. The oxidized hemoglobin forms a heinz body which the spleen pits out, leaving a little bite mark.

Answered 12/9/2013

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Dr. Michael Engel answered

Specializes in Pediatric Hematology and Oncology

Bite cells arise ...: When red cell inclusions called heinz bodies (basically denatured hemoglobin) are removed from rbcs by macrophages as they navigate through the sinusoidal tissue of the spleen. They are not specific to one illness, but rather are associated with many acquired and constitutional conditions. Classically they are seen in innate red cell defects like g6pd deficiency or hemoglobinopathies. Many causes.

Answered 8/26/2015

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