Any known drug interactions between bupropion and diindolylmethane supplements?

Communicate: Before adding a supplement it is a good idea to communicate your intention to the prescribing physician. I am unaware of a specific interaction between this supplement and bupropion. Wellbutrin is not metabolized by cyp 1a2, which appears to be liver enzyme that can be affected by this supplement.

Wellbutrin (bupropion): I am not aware of any, but please talk to your prescribing doctor before adding any supplements.