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Springfield, OH
A 61-year-old male asked:

Is withdrawalease, a substance used for relief of opiate addiction a sham or does it really have beneficial qualities?

3 doctor answers5 doctors weighed in
Dr. John Luther
Addiction Medicine 22 years experience
Opiate withdrawal : I do not know the ingredients of the pills but it does have useful information in the packet. Any help is good help. The best help would be to see a physician and plan a detox that may or may not include trazadone, clonodine, and/or Suboxone to help alleviate the symptoms. Good luck it is one of the most difficult things you will ever do in your life but the rewards are unbelievable if succeed.
Dr. Pamela Pappas
Psychiatry 42 years experience
Withdrawalease: Withdrawalease contains multiple nutritional supplements & herbs, including passion flower and lemon balm (calming nervine herbs). I can find only 1 study using passion flower in opiate withdrawal: http://www.Ncbi.Nlm.Nih.Gov/pubmed/11679027 -- here, adding passion flower to Clonidine was better than Clonidine alone. This is not the same as proving effectiveness of withdrawalease itself.
Dr. David Rosenfeld
Pain Management 27 years experience
No clear evidence: There is no published evidence that it works.
Dr. Pamela Pappas
Psychiatry 42 years experience
There is one published study of one of the ingredients (Passion Flower) in this product -- not the same as a published study of the whole product. One has to be discerning about the interpretations of reports placed on company web sites for such products. Still, Passion Flower is an intriguing herb -- it may act by modulating the GABA system. http://www.ncbi.nlm.nih.gov/pubmed/21089181?log$=activity
Jun 24, 2013

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