There are many cause: For blisters, burn, cold, infection , but the typical casue is mechanical irritation. Many blsiters start with clear fluid then change to a hemmoragic or turbid appeareance. Blisters may also be "superinfected" ie once the skin break is there, local bacteria colonize the tissue. Blood blisters more often come from mechanical trauma though some bacteria and viral blisters get blood in them.
Answered 6/21/2013
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Ganglion: This is probably a ganglion, a fluid-filled cyst. Popping it can cause it to bleed inside, and is rarely helpful. Sometimes popping it can introduce infection. If it starts getting red, you need to have professional look at it.
Answered 9/2/2013
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