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A member asked:
How can chronic kidney disease affect homeostatic mechanisms?
A doctor has provided 1 answer
Too complex: In short, it increases salt and water retention and potassium and magnesium and phosphorus retention depending on degree of ckd. Also increases PTH and decreases vit d due to elevated hormone called fgf 23. Less urine excretion is the reason for the retained electrolytes. Edema and weak bone result & high bp.
Answered 6/10/2014
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