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Dallas, TX
A 45-year-old female asked:

Has anyone seen a patient with adrenal insufficiency, intermittent ovarian failure, intermittent glucose intolerance, and thyroid values in normal range? perhaps also with a pituitary tumor?

2 doctor answers4 doctors weighed in
Dr. Philip Kern
Endocrinology 44 years experience
Pituitary tumors: You need an endocrinologist to sort this out. A big pituitary tumor (>10 mm) can wipe out other hormones; you could lose some (eg reproductive) but not others. Typically the last to go from a pituitary insult is TSH and acth (thyroid and adrenal), but odd things can occur. A micro tumor does not usually damage the rest of the pituitary, but may produce excess hormone (eg. Prolactin, acth).
Dr. Zachary Levine
Neurosurgery 29 years experience
Pituitary tumor: Pituitary tumors can cause endocrine failure or over stimulation depending on their activity. The non secreting tumors usually cause a mild elevation in prolactin but may cause decrease in other hormones. I recommend a hi-res MRI of the brain.
Dr. Samuel Freedman
Pediatrics 10 years experience
Sounds like autoimmune poly glandular failure syndrome. Pituitary can look enlarged due to hypophysitis which is autoimmune as well.
May 19, 2013

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Last updated Jun 10, 2014

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