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Dallas, TX
A 45-year-old female asked:

Has anyone seen a patient with adrenal insufficiency, intermittent ovarian failure, intermittent glucose intolerance, and thyroid values in normal range? perhaps also with a pituitary tumor?

2 doctor answers4 doctors weighed in
Dr. Philip Kern
Endocrinology 43 years experience
Pituitary tumors: You need an endocrinologist to sort this out. A big pituitary tumor (>10 mm) can wipe out other hormones; you could lose some (eg reproductive) but not others. Typically the last to go from a pituitary insult is TSH and acth (thyroid and adrenal), but odd things can occur. A micro tumor does not usually damage the rest of the pituitary, but may produce excess hormone (eg. Prolactin, acth).
Dr. Zachary Levine
Neurosurgery 28 years experience
Pituitary tumor: Pituitary tumors can cause endocrine failure or over stimulation depending on their activity. The non secreting tumors usually cause a mild elevation in prolactin but may cause decrease in other hormones. I recommend a hi-res MRI of the brain.
Dr. Samuel Freedman
Pediatrics 9 years experience
Sounds like autoimmune poly glandular failure syndrome. Pituitary can look enlarged due to hypophysitis which is autoimmune as well.
May 19, 2013

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Last updated Jun 10, 2014

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