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A 32-year-old female asked:

3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. cancer?

2 doctor answers2 doctors weighed in
Dr. David Sneid
Endocrinology 42 years experience
Afirma: You need a repeat biopsy with an afirma assay to screen more critically for possible malignancy. Surgery may be necessary if worrisome changes on ultrasound continue.
Dr. Nagesh Ragavendra
52 years experience
Not necessarily...: The fact that FNA was reported as benign, the nodule is unlikely to be malignant. Small droplets of benign colloid often mimic "microcalcificatins" of papillary tumor, hence caution is advised. I would suggest repeating the FNA, and consider also collecting samples for gene profiling studies, such as, those manufactured by Veracyte and Asuragen (Note:I have no financial/other interest.)

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Last updated Oct 25, 2014

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