A member asked:

Newborn boy has a severe mutation delf508 and a 5-t gt12. was told that he might or might not develop mild cystic fibrosis. how does mild cf manifest?

2 doctors weighed in across 2 answers

Varies: Mild CF can vary from recurrent sinus infections, recurrent pneumonia, pancreatitis, fertility problems. One may have no evidence of CF until adulthood. Sometimes the first sign is recurrent pancreatitis in the second or third decade of life. Usually growth is not impaired.

Answered 3/31/2015

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Dr. Amrita Dosanjh answered

Specializes in Pediatric Allergy and Asthma

Sweat test: It can be difficult to predict the course of CF. If the sweat chloride result is borderline or normal, then typically there are very few or no symptoms.

Answered 3/31/2015

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