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A member asked:

Hla gene mutations predispose one to developing autoimmunity after viral &/or vaccine exposure...why not screen for mutations before vaccinating us?

A doctor has provided 1 answer
Dr. Johanna Fricke answered

Specializes in Pediatrics - Developmental and Behavioral

Vaccine-preventable : Infections trigger clinical symptoms of auto-immune disorders far more often & more severely than do vaccines. The who's criteria for assessing adverse reactions to vaccines, including autoimmune diseases, are the consistency, strength & specificity of an association, not just a temporal relationship. Image.Thelancet.Com/.../02art9340web.Pdf discusses current & future epidemiology

Answered 5/5/2013

5.1k views

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Related Questions

A member asked:

Is the test for HLA-B27 gene a simple YES/NO? Remember my rheumatologist saying "highly elevated". Perhaps inflammation markers or referring to gene?

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A member asked:

Family has Ankylosing Spondylitis(AS) gene, HLA-B27 that comes from dad. Currently mine is inactive. But there is a medicine that could potentially trigger autoimmune disease which I was explained was AS, could mine get triggered by this med if taken?

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A member asked:

If both parents are HLA-B27+ would that guarantee all offspring to have the gene? If so would only 1 positive parent make it a 50% chance?

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Blood tests negative for celiac, hla gene positive, biopsy positive. Could there be another cause for mucosal flattening?

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A member asked:

Why do I have widespread OA at age 36? Mom has aggressive OA/spinal issues. I do not have HLA-B27 gene. Will I be like mom? Have cerv. spondylosis too

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People also searched for:

Why do some people develop autoimmune diseases/disorders after viral exposures, while some people do not? Could hla gene mutations be responsible?
Can mutations in hla genes cause people to be predisposed to possibly developing an autoimmune condition?
Can htlv-1 virus cause mutations to hla genes (mutations that you did not have from birth)?
Shouldn't people be screened for complement system deficiencies and/or dysfunction before being vaccinated? Aren't vaccines harmful to these people?
Will widespread vaccination for 'chickenpox' eventually cause or contribute to a mutation of the virus that is vaccine resistant?

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