Can crohn's disease cause appendicitis? i have a sharp stabbing pain on my lower right side.

Not directly: While patients with crohn's disease can get appendicitis, crohn's does not cause appendicitis. The most common location of intestinal inflammation from crohn's is the terminal ileum, located in the right lower abdomen (near the appendix). Sometimes crohn's can affect the appendix. It can be difficult to differentiate the 2 conditions. Best to see a doctor if you are not improving.